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DermaGenius® 2.0

Detection and identification of dermatophyte infections in nail, hair and skin samples

50 reactions

Products & Targets

Products

PN-301  DermaGenius® 2.0 Nail multiplex kit (50 rxn)  

Targets

  • Candida albicans
  • Trichophyton rubrum
  • Trichophyton interdigitale
  • Internal Control (IC)

PN-401 DermaGenius® 2.0 Complete multiplex kit (50 rxn)

Targets

  • Candida albicans
  • Trichophyton mentagrophytes
  • Trichophyton interdigitale
  • Trichophyton rubrum / soudanense
  • Trichophyton tonsurans
  • Trichophyton violaceum
  • Microsporum canis
  • Microsporum audouinii
  • Epidermophyton floccosum
  • Trichophyton benhamiae
  • Trichophyton verrucosum
  • Internal Control (IC)


Features and benefits

  • Aids in the diagnosis of dermatophytosis (superficial fungal infections)
  • Detects > 95% of the clinically most relevant dermatophytes
  • Detection in nail, skin and hair samples
  • Sample-to-result in less than 3 hours
  • Simple and fast DNA extraction kit included (20 min)
  • Higher sensitivity: up to 20% more positive results compared to culture
  • Dermatophyte species identification, enabling:
  • Targeted treatment
  • Identification of source of infection
  • Outbreak management


Real-time PCR instruments

  • LightCycler 480 II (Roche)
  • Rotor-Gene Q (Qiagen)
  • CFX96 (Biorad)
  • QuantStudio 5 (Thermo Fisher Scientific)
  • Mic qPCR (BMS)


Diagnostic specimens

  • Nail, hair and skin samples
  • Paraffin embedded samples (FFPE)


Quality

  • Validated on clinical samples
  • Internal Control (IC) included
  • Positive Controls (PCs) included
  • Validated on nail, hair and skin samples
  • Validated on EQA programmes of QCMD
  • CE-IVD marked

Background

Dermatophytes represent the most numerous and widespread group of all mycoses and have the capacity to invade keratinized tissue of humans and animals to facilitate infections that are generally restricted to the corneocytes of the skin, hair and nails.
Dermatophytes are classified in three genera: Epidermophyton, Microsporum and Trichophyton. Diagnosis of these infections is currently based on microscopy or histology associated with culture on specific agar media. However, direct microscopy lacks specificity and culturing has a long turn-around-time of 2-4 weeks and is prone to contamination. These limitations can be prevented by the use of molecular diagnostics.

References

Hayette et al., Medical Mycology, 2018; 277–283

Trovato et al., Med Mycol Case Rep., 2019; 24: 72–74

Singh et al., Fungal Genetics and Biology, Vol 133, 2019

PathoNostics Extraction kit

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PN-502 PathoNostics Extraction kit (50 rxn)
  • DNA extraction from nail, hair, skin samples in 20 min

Content

  • Solution A (lysis buffer)
  • Solution B (neutralization buffer)

Quality

  • Validated on fungal cultures
  • Validated on nail, hair, skin samples
  • CE-IVD marked

Please contact us if you need more information.

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