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DermaGenius® 2.0

Detection and identification of dermatophyte infections of nail, hair and skin samples

, 50 reactions

Products & Targets

Products

PN-301  DermaGenius® 2.0 Nail multiplex kit (50 rxn)  

Targets

  • Candida albicans
  • Trichophyton rubrum
  • Trichophyton interdigitale
  • Internal Control (IC)

PN-401 DermaGenius® 2.0 Complete multiplex kit (50 rxn)

Targets

  • Candida albicans
  • Trichophyton mentagrophytes
  • Trichophyton interdigitale
  • Trichophyton rubrum
  • Trichophyton tonsurans
  • Trichophyton soudanense
  • Trichophyton violaceum
  • Microsporum canis
  • Microsporum audouinii
  • Epidermophyton floccosum
  • Trichophyton benhamiae
  • Trichophyton verrucosum
  • Internal Control (IC)


Features and benefits

  • Detects 95% of clinically most prevalent dermatophytes
  • Direct detection of dermatophytes in nail, skin and hair samples
  • Simple and fast DNA extraction included
  • Sample to result within 3 hours for quick and dedicated treatment
  • Higher sensitivity – up to 20% more positive results compared to culture
  • Differentiation of dermatophytes species
  • Identification of source of infection – outbreak management


Real-time PCR instruments

  • LightCycler 480 II (Roche)
  • Rotor-Gene Q (Qiagen)
  • CFX96 (Biorad)
  • Mic qPCR (BMS)
  • QuantStudio 5 (Thermo Fisher Scientific)


Diagnostic specimens

  • Nail samples
  • Hair samples
  • Skin samples


Quality

  • Validated on fungal cultures
  • Validated on nail, hair and skin samples
  • Validated on EQA programmes of QCMD
  • CE-IVD marked

Background

Dermatophytes represent the most numerous and widespread group of all mycoses and have the capacity to invade keratinized tissue of humans and animals to facilitate infections that are generally restricted to the corneocytes of the skin, hair and nails.
Dermatophytes are classified in three genera: Epidermophyton, Microsporum and Trichophyton. Diagnosis of these infections is currently based on microscopy or histology associated with culture on specific agar media. However, direct microscopy lacks specificity and culturing has a long turn-around-time of 2-4 weeks and is prone to contamination. These limitations can be prevented by the use of molecular diagnostics.

References

Hayette et al., Medical Mycology, 2018; 277–283

Trovato et al., Med Mycol Case Rep., 2019; 24: 72–74

PathoNostics Extraction kit

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PN-502 PathoNostics Extraction kit (50 rxn)
  • DNA extraction from nail, hair, skin samples in 20 min

Content

  • Solution A (lysis buffer)
  • Solution B (neutralization buffer)

Quality

  • Validated on fungal cultures
  • Validated on nail, hair, skin samples
  • Validated on EQA programmes of QCMD
  • CE-IVD marked

Please contact us if you need more information.

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